PSP

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Pharmacology

PsP is a Ganoderma lucidum polysaccharide peptide (GLPP) extract from mycelia cell membrane. Each PsP capsule contains250 mg of polysaccharide peptide, in which it has 200 mg β-D-Glucan (180 mg β-1,3/1,6-D-Glucan). β-D-Glucan is an immunomodulator that modulates immune cell activities, especially macrophages.
β-D-Glucan works on several human immune receptors such as Dectin-1 (the main receptor), Toll-like

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Receptor 2 and 6 (TLR-2 and -6), Scavenger Receptor, Complement Receptor 3 (CR3), and Lactosylceramide. It induces a group of immune cells such as macrophages, neutrophils, monocytes, Natural Killer (NK) cells and dendritic cells to modulate the innate and adaptive immune responses.β-D-Glucan is then absorbed by colon peyer patch, and later on phagocyted and degraded by macrophages. Macrophages that contain β-D-Glucan will circulate in the spleen and lymph nodes and release smaller fractions of β-D-Glucan particles to activate other immune cells. In bone marrow these macrophages will also release β-D-Glucan particles to activate bone marrow stem cells.(1,2)

Composition

  • Extract of Ganoderma lucidum polysaccharide peptide (GLPP) ………….
    containing 200 mg β-D-Glucan (180 mg β-1,3/1,6-D-Glucan)
  • Filler up to ……………………………………………………………………………
250

100

mg

mg

Indication

  • To modulate the immune system (immunomodulator) and to be used as a complementary therapy against cancer, cardiovascular diseases, diabetic foot ulcer, and in vascular endothelial disturbances

Contraindication

  • Pregnancy and lactation
  • Children below 5 years old
  • Hypersensitivity

Precaution

  • Stop using when undesirable symptoms occurred. Please consult your doctor

Adverse Reaction

  • Subfebrile and allergic reaction is rare, but can occur in few people (individually)

Dose

  • 1 capsule, 3 times daily

Administration

  • ½ hour before or 2 hours after meals

Storage

  • Keep in dry and cool place, avoid direct sun contact
  • Put in the refrigerator (4-100C) after the seal is opened
  • Keep away from children

Packaging
Box of bottle, 30 capsules @ 250 mg Ganoderma lucidum polysaccharide peptide extract containing 200 mg β-D-Glucan